CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 131 enrolled
Drug / intervention
Conventional neuromuscular blockade +3 moredrug
Likely dose
Conventional neuromuscular blockade 0.4mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02249585
NCT02249585N/ACompleted
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Effects of Neuromuscular Blockade Level and Intra-abdominal Pressure on Surgical Conditions and Cardiopulmonary Responses During Laparoscopic Colon Surgery With the Trendelenburg Position

Seoul National University Hospital·interventional·Posted Sep 25, 2014·Updated Aug 6, 2018

In Brief

A clinical study evaluating Standard abdominal pressure, Low abdominal pressure, and 2 other interventions for Cardiac Index. Completed, enrolled 131 participants across 1 site.

Detailed Summary

The purpose of this study is to find out the effect of low abdominal pressure vs. standard abdominal pressure on the cardiac and respiratory function of the patients undergoing laparoscopic colon surgery in Trendelenberg position. It was also designed to evaluate the effect of the degree of neuromuscular blockade on the surgical condition of the patients undergoing laparoscopic colon surgery in Trendelenberg position.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiac Index
CountriesSouth Korea
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 25, 2014
Enrollment StartSep 1, 2014
Primary CompletionOct 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 11.8 years ago

Interventions

Standard abdominal pressuredevice

Abdominal pressure maintained 12mmHg throughout laparoscopic colon surgery

Low abdominal pressuredevice

Abdominal pressure maintained 8mmHg throughout laparoscopic colon surgery

Conventional neuromuscular blockadedrug

Anesthesia induction with rocuronium 0.4mg/kg and maintenance with rocuronium 0.15mg/kg to maintain TOF 1-2 twitch

Deep neuromuscular blockadedrug

Anesthesia induction with rocuronium 0.8mg/kg → maintenance with rocuronium 0.3mg/kg to maintain PTC 1-2 twitch