At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 6 enrolled
Drug / intervention
IV PBT2 microtracer and oral PBT2 single dose +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase I , Open-Label Study to Evaluate the Absorption, Metabolism and Excretion of [14C]-PBT2 and to Estimate the Absolute Bioavailability of PBT2 in Healthy Male Subjects
In Brief
A Phase 1 clinical trial evaluating IV PBT2 microtracer and oral PBT2 single dose and oral 14C-PBT2 for Healthy Volunteers. Completed, enrolled 6 participants across 1 site.
Detailed Summary
The purpose of the study is to investigate how the test drug, PBT2, is taken up, broken down and removed from the body when given as an oral capsule, a radiolabelled oral suspension and a radiolabelled intravenous injection.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy Volunteers
CountriesUnited Kingdom
Collaborators--
Timeline
Phase 1CompletedFinished
201520162017201820192020202120222023202420252026
Enrollment StartJun 2014
Primary CompletionJul 2014
First PostedSep 2014
TodayJul 2026
First PostedSep 26, 2014
Enrollment StartJun 1, 2014
Primary CompletionJul 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 11.8 years ago
Interventions
IV PBT2 microtracer and oral PBT2 single dosedrug
oral 14C-PBT2drug