CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 146 enrolled
Drug / intervention
Pharmacokineticbiological
Likely dose
Pharmacokinetic 2 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02252237
NCT02252237N/ACompleted
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Study of Pharmacokinetic Variability of Glucocorticoids in Children

Assistance Publique - Hôpitaux de Paris·observational·Posted Sep 30, 2014·Updated Nov 20, 2025

In Brief

An observational study evaluating Pharmacokinetic for Children Receiving Prednisone or Prednisolone or Methylprednisolone or Hydrocortisone. Completed, enrolled 146 participants across 1 site.

Detailed Summary

The purpose of this study is to determine individual susceptibility factors (drug interactions, genetic factors such as enzyme polymorphism…) to explain wide interindividual variability towards corticosteroids (prednisone, prednisolone, methylprednisolone, hydrocortisone) in children, which could establish a base for therapeutic monitoring.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsChildren Receiving Prednisone or Prednisolone or Methylprednisolone or Hydrocortisone
CountriesFrance
CollaboratorsURC-CIC Paris Descartes Necker Cochin

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 30, 2014
Enrollment StartDec 3, 2014
Primary CompletionDec 9, 2021
TodayJul 2, 2026
Enrollment to primary: 7.0 yearsPosted 11.8 years ago

Interventions

Pharmacokineticbiological

Blood sample of 2 ml at enrolment and then at following visits. Buccal cell collection swab