CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 36 enrolled
Drug / intervention
Alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml. +2 moredrug
Likely dose
Alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml.from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02255604
NCT02255604Phase 2Completed
CompareCT.gov

Effect of Intralymphatic Immunotherapy at Basophil Response and Plasmacell Kinetic in Patients With Allergic Rhinitis.

University of Aarhus·interventional·Posted Oct 2, 2014·Updated May 24, 2021

In Brief

A Phase 2 clinical trial evaluating Alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml., alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml., and 1 other intervention for Allergy and 2 related conditions. Completed, enrolled 36 participants across 1 site.

Detailed Summary

The investigators want to investigate whether specific immunotherapy can be delivered directly into a lymph node. The investigators think that a direct introduction of allergen to the antigen presenting cells in the lymph node a give a strong immune response and that this can change the number of injections needed in allergen immunotherapy. The investigators do measurements of clinical effect and a variety of paraclinical test to see if the investigators can find af biomarker of successful specific immune therapy of grass allergy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAllergy, Immune Tolerance, Injection Site Discomfort
CountriesDenmark
Collaborators--

Timeline

Phase 2CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedOct 2, 2014
Enrollment StartAug 1, 2013
Primary CompletionSep 1, 2015
Study CompletionFeb 1, 2017
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 11.8 years ago

Interventions

Alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml.drug

4

alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml.drug

3 injection into a lymphnode

0.1 ml Isoton salinedrug

4 injection into a lymphnode