CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 26 enrolled / 26 target
Drug / intervention
Nivolumab +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02257528
NCT02257528Phase 2ActiveUpdate Overdue (0.2/mo)Completion was 87mo ago

A Phase II Evaluation of Nivolumab, a Fully Human Antibody Against PD-1, in the Treatment of Persistent or Recurrent Cervical Cancer

National Cancer Institute (NCI)·interventional·Posted Oct 6, 2014·Updated Jun 17, 2026

In Brief

A Phase 2 clinical trial evaluating Laboratory Biomarker Analysis and Nivolumab for Cervical Adenocarcinoma and 5 related conditions. Active but no longer recruiting, targeting 26 participants across 332 sites.

Signals

Enrollment appears stalled

Detailed Summary

This phase II trial studies the side effects and how well nivolumab works in treating patients with cervical cancer that has grown, come back, or spread to other places in the body. Monoclonal antibodies, such as nivolumab, may block tumor growth in different ways by targeting certain cells.

Study Details

Timeline

Phase 2Active
2015201620172018201920202021202220232024202520262027
First PostedOct 6, 2014
Enrollment StartMay 18, 2015
Primary CompletionMar 5, 2019
Study CompletionMar 30, 2027
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 11.7 years ago

Arms & Interventions

Treatment (nivolumab)experimental

Patients receive nivolumab IV over approximately 60 minutes every 2 weeks for a maximum of 46 doses over 92 weeks in the absence of disease progression or unacceptable toxicity.

Other: Laboratory Biomarker AnalysisBiological: Nivolumab

Interventions

Laboratory Biomarker Analysisother

Correlative studies

Nivolumabbiological

Given IV