At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 41 enrolled
Drug / intervention
Minocyclinedrug
Likely dose
Minocycline 200mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Minocycline as an Adjunct for the Treatment of Depressive Symptoms: Pilot Randomized Controlled Trial
In Brief
A Phase 4 clinical trial evaluating Minocycline for Depressive Disorder and 3 related conditions. Completed, enrolled 41 participants across 3 sites.
Detailed Summary
In this double blind randomised controlled pilot trial the investigators aim to determine the efficacy of minocycline as an adjunct to treatment as usual in patients with major depressive disorder. The investigators hypothesize that the multiple neuroprotective effects of minocycline will lead to an improvement in depressive symptoms in participants that were given minocycline plus treatment as usual
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepressive Disorder, Mood Disorders, Depressive Disorder, Treatment Resistant, Antidepressive Agents
CountriesPakistan
CollaboratorsKing's College London
Timeline
Phase 4CompletedFinished
201520162017201820192020202120222023202420252026
Enrollment StartOct 2014
First PostedOct 2014
Primary CompletionJun 2016
Study CompletionAug 2016
TodayJul 2026
First PostedOct 13, 2014
Enrollment StartOct 1, 2014
Primary CompletionJun 1, 2016
Study CompletionAug 1, 2016
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 11.7 years ago
Interventions
Minocyclinedrug
Minocycline 200mg perday