At a glance

ClinicalIndex Comparison Record

N/ACompleted· 15 enrolled

Drug / intervention

[15O]H2O PET-CT scan +1 moreother

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02272985

NCT02272985N/ACompleted

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A [15O]H2O PET-CT Pilot Study Comparing Cerebral Blood Flow Before, During and After Hemodialysis

University Medical Center Groningen·interventional·Posted Oct 23, 2014·Updated Apr 7, 2020

In Brief

A clinical study evaluating [15O]H2O PET-CT scan and NIRS (Invos) for Haemodialysis-induced Symptom. Completed, enrolled 15 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the effect of the hemodialysis procedure on cerebral blood flow (CBF) in elderly maintenance hemodialysis (HD) patients. The investigators hypothesize that HD induced blood pressure changes are associated with a fall in global and/or regional CBF during HD. Second, the investigators hypothesize that near infrared spectroscopy (NIRS) will correlate with CBF measured by\[15O\]H2O PET.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsHaemodialysis-induced Symptom

CountriesNetherlands

CollaboratorsMartini Hospital Groningen

Timeline

N/ACompletedFinished

201520162017201820192020202120222023202420252026

First PostedOct 2014

Enrollment StartApr 2015

Primary CompletionNov 2015

TodayJul 2026

First PostedOct 23, 2014

Enrollment StartApr 1, 2015

Primary CompletionNov 1, 2015

TodayJul 2, 2026

Enrollment to primary: 7 monthsPosted 11.7 years ago

Interventions

[15O]H2O PET-CT scanother

All participants will undergo 3 \[15O\]H2O PET-CT scans during the hemodialysis study session

NIRS (Invos)other

All participants will undergo near infrared spectroscopy (NIRS) during the hemodialysis study session.