CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 114 enrolled
Drug / intervention
blood samplingbiological
Likely dose
blood sampling 4 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02274402
NCT02274402N/ACompleted
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Study of Pharmacokinetic and Pharmacodynamic Variability of Prednisone, in Adults

Assistance Publique - Hôpitaux de Paris·observational·Posted Oct 24, 2014·Updated Nov 20, 2025

In Brief

An observational study evaluating blood sampling for Patients Receiving Prednisone. Completed, enrolled 114 participants across 1 site.

Detailed Summary

This is a monocentric study, in the Internal Medicine Service of Cochin Hospital, Paris. Our main objective is to determine the pharmacokinetic properties of prednisone, secondary objectives are to determine the covariates affecting the prednisone pharmacokinetics and the relationship between glucocorticoid exposition levels and their side effects. The investigators will use a prospective, observational, population pharmacokinetic approach. 100 patients starting a prednisone treatment \>7,5mg/d for an expected period \>3 months will be recruited and followed over 6 months.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsPatients Receiving Prednisone
CountriesFrance
CollaboratorsURC-CIC Paris Descartes Necker Cochin

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedOct 24, 2014
Enrollment StartNov 1, 2014
Primary CompletionNov 1, 2015
Study CompletionJun 1, 2016
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 11.7 years ago

Interventions

blood samplingbiological

Blood sample of 4 ml at enrolment and then at two following visits