CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 39 enrolled
Drug / intervention
Aerobic Exercise +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02276079
NCT02276079N/ACompleted
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The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury

University of Florida·interventional·Posted Oct 27, 2014·Updated Dec 4, 2018

In Brief

A clinical study evaluating Aerobic Exercise and Non-Aerobic Exercise for Brain Concussion. Completed, enrolled 39 participants across 1 site.

Detailed Summary

The study is a "proof-of-principle" project to examine the safety and feasibility of implementing a 1-week aerobic exercise program in the post-acute phase after mild traumatic brain injury (mTBI). The study will define the extent to which the exercise program improves recovery from mTBI in terms of relevant functional outcomes (cognition, mood, and physical status) and biomarkers (peripheral brain-derived neurotrophic factor \[BDNF\] concentration).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBrain Concussion
CountriesUnited States
CollaboratorsClinical & Translational Science Institute, American Psychological Foundation, American Psychological Association (APA)

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedOct 27, 2014
Enrollment StartFeb 17, 2015
Primary CompletionDec 22, 2016
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 11.7 years ago

Interventions

Aerobic Exercisebehavioral

Aerobic exercise will consist of riding a stationary bicycle at moderate intensity for 2 consecutive, 20-minute periods with a 5-minute break in between. Moderate intensity is defined as maintaining 65-75% of estimated maximum heart rate based on the calculation (HRmax = 208 - 0.7 × age).

Non-Aerobic Exercisebehavioral

Non-Aerobic exercise will consist of very low-intensity movements including static stretching and toning exercises.Participants will complete 2 consecutive, 20-minute periods with a 5-minute break in between, mirroring the aerobic exercise condition. Heart rate will be monitored by research staff to ensure that it remains below 50% of estimated maximum heart rate.