CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 120 enrolled
Drug / intervention
Tedizolid Phophate +3 moredrug
Likely dose
Tedizolid Phophate 200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02276482
NCT02276482Phase 3Completed

Phase 3 Study of IV to Oral 6-Day Tedizolid Phosphate Compared With 10-day Comparator in Subjects 12 to < 18 Years With cSSTI.

Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)·interventional·Posted Oct 28, 2014·Updated Aug 7, 2019

In Brief

A Phase 3 clinical trial evaluating Tedizolid Phophate, Antibiotic comparator, and 2 other interventions for Skin Diseases, Infectious and Skin Diseases, Bacterial. Completed, enrolled 120 participants.

Detailed Summary

The purpose of the study is to compare the safety of intravenous (IV) and/or oral 6-day 200 mg tedizolid phosphate with 10-day comparator in participants 12 to \<18 years with cSSTI.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedOct 28, 2014
Enrollment StartMar 25, 2015
Primary CompletionSep 17, 2018
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 11.7 years ago

Interventions

Tedizolid Phophatedrug

Tedizolid Phophate 200 mg, IV and/or oral for 6 days

Antibiotic comparatordrug

Antibiotic comparator drug, IV and/or orally for 10 days. Antibiotic comparator included the following: Vancomycin, Linezolid, Clindamycin, Flucloxacillin, Cefazolin, Cephalexin.

Aztreonamdrug

In countries and/or sites where aztreonam is available, adjunctive aztreonam (IV) may be initiated on Day 1 or during the first 3 days of treatment if the participant is determined or suspected to have an infection with gram-negative aerobic pathogens.

Metronidazoledrug

Metronidazole (IV or oral) may be initiated on Day 1 or during the first 3 days of treatment if the participant is determined or suspected to have an infection with anaerobic pathogens.