CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 204 enrolled
Drug / intervention
Polytetrafluoroethylene +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02277925
NCT02277925N/ACompleted

Permanent Versus Delayed-absorbable Monofilament Suture for Vaginal Graft Attachment During Minimally-invasive Total Hysterectomy and Sacrocolpopexy: A Randomized Clinical Trial

University of North Carolina, Chapel Hill·interventional·Posted Oct 29, 2014·Updated Nov 19, 2019

In Brief

A clinical study evaluating Polytetrafluoroethylene and Polydioxanone for Pelvic Organ Prolapse. Completed, enrolled 204 participants across 5 sites.

Detailed Summary

Primary Aim: The primary aim of this randomized controlled trial (RCT) is to compare vaginal mesh and suture exposure rates in women undergoing robotic total hysterectomy and sacrocolpopexy with a light-weight polypropylene mesh (Upsylon™ y-mesh) using permanent (polytetrafluoroethylene, Gore-Tex) versus delayed absorbable monofilament (2-0 polydioxanone, PDS) sutures through 1-year. Secondary Aims: 1. To compare the 1-year composite success rate (leading edge of prolapse is at or above the hymen and apex has descended less than 1/3 of the vaginal length, no subjective feeling of bulge; and no retreatment for pelvic organ prolapse (POP) or vaginal mesh exposure) of permanent versus delayed absorbable sutures for mesh graft attachment during robotic total hysterectomy and sacrocolpopexy. 2. To evaluate adverse outcomes in each group

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedOct 29, 2014
Enrollment StartApr 7, 2015
Primary CompletionOct 7, 2019
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 11.7 years ago

Interventions

Polytetrafluoroethyleneother

Suture used to attach mesh during sacral colpopexy surgery

Polydioxanoneother

Suture used to attach mesh during sacral colpopexy surgery