CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 24 enrolled
Drug / intervention
Human Plasma-Derived Fibrinogen Concentratebiological
Likely dose
Human Plasma-Derived Fibrinogen Concentrate 1 gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02281500
NCT02281500Phase 2Completed

Multicenter, Prospective, Open-Label, Single-Arm Trial to Evaluate the Pharmacokinetics, Efficacy, and Safety of Human Plasma-Derived Fibrinogen (FIB Grifols) in Patients With Congenital Afibrinogenemia

Grifols Therapeutics LLC·interventional·Posted Nov 3, 2014·Updated Mar 31, 2022

In Brief

A Phase 2 clinical trial evaluating Human Plasma-Derived Fibrinogen Concentrate for Congenital Afibrinogenemia. Completed, enrolled 24 participants across 6 sites in 4 countries.

Detailed Summary

The main objective of this study was to evaluate the pharmacokinetics (PK), efficacy, and safety of human plasma-derived fibrinogen concentrate FIB Grifols after a single-dose 70 milligrams/kilogram (mg/kg) body weight administration.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndia, Italy, Lebanon, United States

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedNov 3, 2014
Enrollment StartJul 22, 2016
Primary CompletionNov 11, 2019
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 11.7 years ago

Interventions

Human Plasma-Derived Fibrinogen Concentratebiological

A sterile freeze-dried fibrinogen concentrate filled in vials containing 1 g of FIB Grifols. FIB Grifols contains 20 mg/ml of active substance fibrinogen when reconstituted.