At a glance
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Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE
In Brief
A clinical study evaluating Enhanced oropharyngeal suction and Usual Care for Respiratory Failure. Completed, enrolled 513 participants across 1 site.
Detailed Summary
Insertion of a breathing tube to enable treatment with mechanical ventilation (respirator) is often associated with complications, such as infection and lung injury. Leakage of secretions around the breathing tube (microaspiration) is a major factor leading to complications. The investigators propose that a standardized, enhanced oral suction protocol will be effective in reducing microaspiration and harms associated with mechanical ventilation. The investigators hypothesize that those randomized to the enhanced oral suction protocol will have less microaspiration and other ventilator-associated conditions than those in the usual care, standard suction group.
Study Details
Timeline
Interventions
Deep oropharyngeal suction with catheter every 4 hours
Oral suction with suction swab every 4 hours