CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 513 enrolled
Drug / intervention
Enhanced oropharyngeal suction +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02284178
NCT02284178N/ACompleted

Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE

University of Central Florida·interventional·Posted Nov 5, 2014·Updated Aug 15, 2019

In Brief

A clinical study evaluating Enhanced oropharyngeal suction and Usual Care for Respiratory Failure. Completed, enrolled 513 participants across 1 site.

Detailed Summary

Insertion of a breathing tube to enable treatment with mechanical ventilation (respirator) is often associated with complications, such as infection and lung injury. Leakage of secretions around the breathing tube (microaspiration) is a major factor leading to complications. The investigators propose that a standardized, enhanced oral suction protocol will be effective in reducing microaspiration and harms associated with mechanical ventilation. The investigators hypothesize that those randomized to the enhanced oral suction protocol will have less microaspiration and other ventilator-associated conditions than those in the usual care, standard suction group.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedNov 5, 2014
Enrollment StartAug 1, 2014
Primary CompletionAug 1, 2017
Study CompletionDec 1, 2017
TodayJul 2, 2026
Enrollment to primary: 3 yearsPosted 11.7 years ago

Interventions

Enhanced oropharyngeal suctionother

Deep oropharyngeal suction with catheter every 4 hours

Usual Careother

Oral suction with suction swab every 4 hours