CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 395 enrolled
Drug / intervention
Enzalutamide +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02294461
NCT02294461Phase 3Completed

Asian Multinational Phase 3, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Oral Enzalutamide in Chemotherapy Naïve Subjects With Progressive Metastatic Prostate Cancer Who Have Failed Androgen Deprivation Therapy

Astellas Pharma Inc·interventional·Posted Nov 19, 2014·Updated Oct 24, 2025

In Brief

A Phase 3 clinical trial evaluating Enzalutamide and Placebo for Progressive Metastatic Prostate Cancer. Completed, enrolled 395 participants across 47 sites in 4 countries.

Detailed Summary

Purpose of the study was to assess the effect of enzalutamide on time to Prostate Specific Antigen (PSA) progression as compared to placebo in chemotherapy naïve participants with progressive metastatic prostate cancer who have failed androgen deprivation therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina, Hong Kong, South Korea, Taiwan
Collaborators--

Timeline

Phase 3CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedNov 19, 2014
Enrollment StartApr 23, 2014
Primary CompletionSep 20, 2015
Study CompletionJul 17, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 11.6 years ago

Interventions

Enzalutamidedrug

Oral

Placebodrug

Oral