At a glance
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Pilot Clinical Trial Evaluating the Utility of Minocycline as an Agent to Decrease Chemotherapy-Induced Peripheral Neuropathy (CIPN) and Paclitaxel-Induced Acute Pain Syndrome (P-APS): A Randomized Placebo-Controlled, Double Blind Trial
In Brief
A Phase 2 clinical trial evaluating Minocycline Hydrochloride, Placebo, and 2 other interventions for Acute Pain and 2 related conditions. Completed, enrolled 47 participants across 12 sites.
Detailed Summary
This randomized pilot trial studies how well minocycline hydrochloride works in reducing chemotherapy-induced peripheral neuropathy and acute pain in patients with breast cancer undergoing treatment with paclitaxel. Drugs used in chemotherapy, such as paclitaxel, may cause damage to nerves that result in aches, pains, and tingling or numbness of fingers and toes. Minocycline hydrochloride may help lessen nerve damage from paclitaxel and improve the quality of life in breast cancer patients.
Study Details
Timeline
Interventions
Given PO
Given PO
Ancillary studies
Ancillary studies