CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 21 enrolled
Drug / intervention
Cabozantinib S-malate +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02302833
NCT02302833Phase 2Completed

A Phase II Study to Evaluate the Effects of Cabozantinib in Patients With Unresectable Metastatic Pheochromocytomas and Paragangliomas

M.D. Anderson Cancer Center·interventional·Posted Nov 27, 2014·Updated Jul 31, 2025

In Brief

A Phase 2 clinical trial evaluating Cabozantinib S-malate, Laboratory Biomarker Analysis, and 1 other intervention for Locally Advanced Paraganglioma and 5 related conditions. Completed, enrolled 21 participants across 1 site.

Detailed Summary

This pilot phase II trial studies how well cabozantinib s-malate works in treating patients with pheochromocytomas or paragangliomas that have spread from the primary site to other places in the body and cannot be removed by surgery. Cabozantinib s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking the growth of new blood vessels necessary for tumor growth.

Study Details

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedNov 27, 2014
Enrollment StartFeb 17, 2015
Primary CompletionNov 12, 2024
TodayJul 2, 2026
Enrollment to primary: 9.7 yearsPosted 11.6 years ago

Interventions

Cabozantinib S-malatedrug

Given PO

Laboratory Biomarker Analysisother

Correlative studies

Questionnaire Administrationother

Ancillary studies