At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 109 enrolled
Drug / intervention
Metformin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Novel Actions of Metformin to Augment Resistance Training Adaptations in Older Adults
In Brief
A Early Phase 1 clinical trial evaluating Progressive Resistance Training and Metformin for Aging. Completed, enrolled 109 participants across 2 sites.
Detailed Summary
The purpose of this study is to determine whether a commonly prescribed drug, metformin, can enhance the benefits seen during resistance exercise such as increased muscle mass and strength.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAging
CountriesUnited States
CollaboratorsUniversity of Alabama at Birmingham
Timeline
Early Ph 1CompletedFinished
201520162017201820192020202120222023202420252026
First PostedDec 2014
Enrollment StartJan 2015
Primary CompletionDec 2017
Study CompletionJun 2018
TodayJul 2026
First PostedDec 4, 2014
Enrollment StartJan 14, 2015
Primary CompletionDec 14, 2017
Study CompletionJun 28, 2018
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 11.6 years ago
Interventions
Progressive Resistance Trainingbehavioral
Participants will complete 14 weeks (42 sessions, 3x/week) of progressive resistance training which will consist of 8 constant load movements to train all major muscle groups bilaterally.
Metformindrug
Participants will be randomized to receive metformin in conjunction with their strength training program.