CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 192 enrolled
Drug / intervention
CNTO 1959 50 mg +3 moredrug
Likely dose
CNTO 1959 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02325219
NCT02325219Phase 3Completed

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of CNTO 1959 (Guselkumab) in the Treatment of Subjects With Moderate to Severe Plaque-type Psoriasis

Janssen Pharmaceutical K.K.·interventional·Posted Dec 24, 2014·Updated May 22, 2020

In Brief

A Phase 3 clinical trial evaluating CNTO 1959 50 mg, CTNO 1959 100 mg, and 2 other interventions for Psoriasis. Completed, enrolled 192 participants across 27 sites.

Detailed Summary

The purpose of this study is to demonstrate the superiority of CNTO 1959 (guselkumab) to placebo in the treatment of participants with moderate to severe plaque-type psoriasis (A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPsoriasis
CountriesJapan
Collaborators--

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedDec 24, 2014
Enrollment StartDec 19, 2014
Primary CompletionMar 2, 2016
Study CompletionFeb 8, 2019
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 11.5 years ago

Interventions

CNTO 1959 50 mgdrug

Participants will receive subcutaneous injection of CNTO 1959 50 mg.

CTNO 1959 100 mgdrug

Participants will receive subcutaneous injection of CNTO 1959 100 mg.

Placebo 50 mgdrug

Participants will receive subcutaneous injection of Placebo matched to CNTO 1959 50 mg.

Placebo 100 mgdrug

Participants will receive subcutaneous injection of Placebo matched to CNTO 1959 100 mg.