CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 54 enrolled
Drug / intervention
Methylphenidate HCl +1 moredrug
Likely dose
Methylphenidate HCl 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02327195
NCT02327195Phase 1Completed
CompareCT.gov

Active Emergence of From Isoflurane General Anesthesia Induced by Methylphenidate

Nicoleta Stoicea·interventional·Posted Dec 30, 2014·Updated Jul 12, 2022

In Brief

A Phase 1 clinical trial evaluating Methylphenidate HCl and Placebo for Delayed Emergence From Anesthesia. Completed, enrolled 54 participants across 1 site.

Detailed Summary

The purpose of this study is to assess whether methylphenidate affects time of emergence from isoflurane general anesthesia. Time to emergence was defined as the time from termination of isoflurane to extubation. After stopping isoflurane infusion, when the patient breaths spontaneously with adequate tidal volume and respiratory rates, the trachea will be extubated and the time will be recorded.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDelayed Emergence From Anesthesia
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedDec 30, 2014
Enrollment StartMay 1, 2014
Primary CompletionJan 1, 2018
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 11.5 years ago

Interventions

Methylphenidate HCldrug

Subjects will be randomly assigned to either the Methylphenidate or the Placebo arm, and be given a 20 mg dose (of Methylphenidate or Placebo) in liquid form (4 mL)

Placebodrug

20 mg of placebo (PO) will be given 2 hours prior to surgery