CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 45 enrolled
Drug / intervention
Cenicriviroc 150 mg +1 moredrug
Likely dose
Cenicriviroc 150 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02330549
NCT02330549Phase 2Completed

ORION - Effect of CCR2 and CCR5 Antagonism by Cenicriviroc on Peripheral and Adipose Tissue Insulin Sensitivity in Adult Obese Subjects With Prediabetes or Type 2 Diabetes Mellitus and Suspected Non-Alcoholic Fatty Liver Disease (NAFLD)

Tobira Therapeutics, Inc.·interventional·Posted Jan 5, 2015·Updated Oct 11, 2019

In Brief

A Phase 2 clinical trial evaluating Cenicriviroc 150 mg and Placebo for Prediabetic State and 2 related conditions. Completed, enrolled 45 participants across 3 sites in 2 countries.

Detailed Summary

A Phase 2a, randomized, double-blind, placebo-controlled, multi-center study of cenicriviroc (CVC) to be conducted in approximately 50 adult obese subjects \[body mass index (BMI) ≥ 30 kg/m\^2\] with prediabetes or type 2 diabetes mellitus and suspected NALFD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesPuerto Rico, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedJan 5, 2015
Enrollment StartJul 17, 2015
Primary CompletionAug 11, 2016
Study CompletionSep 8, 2016
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 11.5 years ago

Interventions

Cenicriviroc 150 mgdrug

Cenicriviroc (CVC) 150 mg, administered orally once daily and taken every morning with food.

Placebodrug

Placebo-matching CVC administered orally once daily and taken every morning with food.