CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 134 enrolled
Drug / intervention
Methylprednisolone +1 moredrug
Likely dose
Methylprednisolone 125 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02332603
NCT02332603Phase 3Completed
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Effect of Preoperative Intravenous High Dose Methylprednisolone on Glucose Homeostasis in Patients Scheduled for Total Hip- and Knee-arthroplasty

Rigshospitalet, Denmark·interventional·Posted Jan 7, 2015·Updated Jan 18, 2017

In Brief

A Phase 3 clinical trial evaluating Methylprednisolone and Isotonic Sodium Chloride for Osteoarthrosis. Completed, enrolled 134 participants across 1 site.

Detailed Summary

This study evaluates the pathophysiological effects of a single dose of Methylprednisolone administered prior to total hip- and knee-arthroplasty surgery. The investigators examine the effect on blood glucose homeostasis. Half of participants will receive intravenous Solu-Medrol 125 mg, while the other half will receive placebo. The investigators hypothesize that the glucose homeostasis remains equally stable in the group receiving Methylprednisolone as in the group receiving placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthrosis
CountriesDenmark
CollaboratorsBispebjerg Hospital

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedJan 7, 2015
Enrollment StartJan 1, 2015
Primary CompletionJan 1, 2017
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 11.5 years ago

Interventions

Methylprednisolonedrug

Comparison of preoperative single high dose of Methylprednisolone 125 mg iv. and isotonic Sodium Chloride

Isotonic Sodium Chloridedrug

Placebo