CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 19 enrolled
Drug / intervention
GHB 35 mg/kg p.o. +1 moredrug
Likely dose
GHB 35 mg/kg p.o.from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02342366
NCT02342366N/ACompleted
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Multimodal Characterization of the Prosocial and Prosexual Effects of GHB Assessing Behavior, fMRI, EEG, and Neuroendocrine Mechanisms

University of Zurich·interventional·Posted Jan 19, 2015·Updated Jul 29, 2019

In Brief

A clinical study evaluating GHB 35 mg/kg p.o. and GHB 20 mg/kg p.o. for Depressive Disorder, Major and 2 related conditions. Completed, enrolled 19 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether gamma-Hydroxybutyrate (GHB) has prosocial and prosexual effects in healthy male participants, and to characterize these putative effects via behavioral tests, functional magnetic resonance imaging (fMRI), electroencephalography (EEG), and neuroendocrine parameters. The investigators predict that GHB in fact has prosocial and prosexual effects which can be neurobiologically characterized using the assessed methods. Such effects would be of high interest for the treatment of mental disorders which involve impairments of social interaction and sexual function such as major depression or autism.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepressive Disorder, Major, Bipolar Disorder, Autistic Disorder
CountriesSwitzerland
CollaboratorsUniversity of Regensburg, University of Salerno, University of Vienna, University of Freiburg

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedJan 19, 2015
Enrollment StartFeb 1, 2012
Primary CompletionNov 1, 2014
Study CompletionDec 1, 2014
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 11.5 years ago

Interventions

GHB 35 mg/kg p.o.drug

GHB 35 mg/kg p.o.

GHB 20 mg/kg p.o.drug

GHB 20 mg/kg p.o.