CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 70 enrolled
Drug / intervention
Cediranib Maleate +8 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02345265
NCT02345265Phase 2Active
CompareCT.gov

A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian Cancer

National Cancer Institute (NCI)·interventional·Posted Jan 26, 2015·Updated May 28, 2026

In Brief

A Phase 2 clinical trial evaluating Biopsy Procedure, Biospecimen Collection, and 7 other interventions for Fallopian Tube Carcinoma and 8 related conditions. Active but no longer recruiting, targeting 70 participants across 20 sites.

Detailed Summary

This phase II trial studies how well olaparib and cediranib maleate work in treating patients with ovarian, primary peritoneal, or fallopian tube cancer that has come back after a period of improvement (recurrent). Olaparib and cediranib maleate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFallopian Tube Carcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Ovarian Carcinoma, Ovarian High Grade Endometrioid Adenocarcinoma, Ovarian High Grade Serous Adenocarcinoma, Primary Peritoneal Carcinoma, Primary Peritoneal Endometrioid Adenocarcinoma, Primary Peritoneal Serous Adenocarcinoma
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
2015201620172018201920202021202220232024202520262027
First PostedJan 26, 2015
Enrollment StartMay 23, 2016
Primary CompletionJul 7, 2022
Study CompletionMar 4, 2027
TodayJul 2, 2026
Enrollment to primary: 6.1 yearsPosted 11.4 years ago

Interventions

Biopsy Procedureprocedure

Undergo biopsy of tumor

Biospecimen Collectionprocedure

Undergo blood sample collection

Cediranib Maleatedrug

Given PO

Computed Tomographyprocedure

Undergo CT scan

Echocardiography Testprocedure

Undergo echocardiogram

Magnetic Resonance Imagingprocedure

Undergo MRI scan

Multigated Acquisition Scanprocedure

Undergo MUGA

Olaparibdrug

Given PO

Questionnaire Administrationother

Ancillary studies