CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 40 enrolled
Drug / intervention
Sirolimus +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02357342
NCT02357342Phase 2Completed

Sirolimus Versus AntiVEGF for Wet AMD

Maturi, Raj K., M.D., P.C.·interventional·Posted Feb 6, 2015·Updated Jun 22, 2017

In Brief

A Phase 2 clinical trial evaluating Sirolimus and Standard of Care intravitreal injections of anti-VEGF for Age-Related Macular Degeneration. Completed, enrolled 40 participants across 1 site.

Detailed Summary

Phase 2 clinical trial, single site, randomized, subject-masked study to determine safety and efficacy of intravitreal injections of Sirolimus in subjects with wet Age-Related Macular Degeneration (wet AMD) with persistent intraretinal or subretinal edema due to neovascular AMD despite previous AntiVEGF treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedFeb 6, 2015
Enrollment StartApr 1, 2015
Primary CompletionJan 1, 2017
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 11.4 years ago

Interventions

Sirolimusdrug

intravitreal injection

Standard of Care intravitreal injections of anti-VEGFdrug

intravitreal injections of anti-VEGF