CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 201 enrolled
Drug / intervention
methenamine hippurate +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02358993
NCT02358993N/ACompleted
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The Efficacy and Cost-effectiveness of a 24-hour Course of metheNamine Hippurate for Preventing Post-Operative Urinary Tract Infection

University of Pennsylvania·interventional·Posted Feb 9, 2015·Updated Feb 25, 2022

In Brief

A clinical study evaluating methenamine hippurate and Ciprofloxacin for Urinary Tract Infections and Catheter-Related Infections. Completed, enrolled 201 participants across 4 sites.

Detailed Summary

The investigators will determine the efficacy of an innovative short regimen of methenamine hippurate on prevention of post-operative UTI in patients requiring short-term catheterization after pelvic reconstructive surgery through a single-blind, randomized controlled trial. Primary outcome will be the rate of symptomatic UTI within 3 weeks of catheter removal. The investigators will study cost-effectiveness, antibiotic resistance profiles, and adverse drug effects. Findings may reduce antibiotic use and nosocomial UTIs.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsUrinary Tract Infections, Catheter-Related Infections
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedFeb 9, 2015
Enrollment StartDec 1, 2014
Primary CompletionSep 30, 2020
TodayJul 2, 2026
Enrollment to primary: 5.8 yearsPosted 11.4 years ago

Interventions

methenamine hippuratedrug

A urinary antiseptic used for prevention of UTI

Ciprofloxacindrug

An antibiotic used for treatment and prevention of UTI