At a glance

ClinicalIndex Comparison Record

N/ACompleted· 17 enrolled

Drug / intervention

Analgesia Nociception Indexdevice

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02364856

NCT02364856N/ACompleted

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Assessment of Pain Through Parasympathetic Tone Analysis : Applicability in Children With Cerebral Palsy.

University Hospital, Lille·observational·Posted Feb 18, 2015·Updated Apr 17, 2026

In Brief

An observational study evaluating Analgesia Nociception Index for Cerebral Palsy and 2 related conditions. Completed, enrolled 17 participants across 3 sites.

Detailed Summary

This study evaluates Analgesia Nociception Index (Heart Rate Variability based index) and its variations after painful stimulations in children with cerebral palsy : acute procedural pain (botulinum toxin injections), and recurrent pain (physiotherapy).

Study Details

Study Typeobservational

Allocation--

Masking--

Primary Purpose--

ConditionsCerebral Palsy, Pain, Children

CountriesFrance

CollaboratorsClinical Investigation Centre for Innovative Technology Network, Fondation Motrice

Timeline

N/ACompletedFinished

201520162017201820192020202120222023202420252026

First PostedFeb 2015

Enrollment StartApr 2015

Primary CompletionApr 2018

TodayJul 2026

First PostedFeb 18, 2015

Enrollment StartApr 24, 2015

Primary CompletionApr 12, 2018

TodayJul 2, 2026

Enrollment to primary: 3.0 yearsPosted 11.4 years ago

Interventions

Analgesia Nociception Indexdevice

The Analgesia Nociception Index (ANI, MDoloris Medical Systems, Lille, France), based on Heart Rate Variability analysis, measures continuously and non-invasively the influence of Respiratory Sinus Arrhythmia on the heart rate. This 0-100 index indicates the proportion of paraS over sympathetic activity. In adults during surgery under general anesthesia, ANI decreases after painful stimulation and has been related to the balance between analgesia and nociception. ANI is calculated from heart rate recording.