At a glance
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Phase I Trial of Berberine in Subjects With Ulcerative Colitis
In Brief
A Phase 1 clinical trial evaluating Berberine Chloride, Laboratory Biomarker Analysis, and 1 other intervention for Ulcerative Colitis. Completed, enrolled 18 participants across 2 sites in 2 countries.
Detailed Summary
This randomized, pilot phase I trial studies the side effects of berberine chloride in treating patients with ulcerative colitis and who are in remission (a decrease in or disappearance of signs and symptoms of cancer) to reduce the risk of colorectal cancer. Patients with ulcerative colitis are at increased risk for colorectal cancer. Chemoprevention is the use of drugs, such as berberine chloride, to keep a disease/condition from forming or coming back. The use of berberine chloride may keep colorectal cancer from forming in patients with ulcerative colitis.
Study Details
Timeline
Interventions
Given PO
Correlative studies
Given PO