At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 34 enrolled
Drug / intervention
TAK-272 +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase 1, Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of TAK-272 and the Effect of TAK-272 on the Pharmacokinetics of Digoxin or Midazolam In the Healthy Adult Participants
In Brief
A Phase 1 clinical trial evaluating TAK-272, Digoxin, and 2 other interventions for Japanese Healthy Adult Males. Completed, enrolled 34 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate the effect of repeated-dose administration of itraconazole on the pharmacokinetics of TAK-272, as well as the effect of repeated-dose administration of TAK-272 on the pharmacokinetics of digoxin or midazolam in healthy Japanese adult males.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsJapanese Healthy Adult Males
CountriesJapan
Collaborators--
Timeline
Phase 1CompletedFinished
201520162017201820192020202120222023202420252026
Enrollment StartFeb 2015
First PostedFeb 2015
Primary CompletionApr 2015
TodayJul 2026
First PostedFeb 25, 2015
Enrollment StartFeb 1, 2015
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 11.4 years ago
Interventions
TAK-272drug
TAK-272 tablet.
Digoxindrug
Digoxin tablet.
Itraconazoledrug
Itraconazole oral solution
Midazolamdrug
Midazolam syrup.