CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 256 enrolled
Drug / intervention
L+C maxillary anesthesia +3 moredrug
Likely dose
L+C maxillary anesthesia 15 mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02371759
NCT02371759Phase 3Completed
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Efficacy and Safety of Intraoral Local Anesthesia by Lidocaine + Clonidine in Patients With Diabetes Mellitus Type 2

University of Belgrade·interventional·Posted Feb 26, 2015·Updated May 3, 2017

In Brief

A Phase 3 clinical trial evaluating L+C maxillary anesthesia, L+C mandibular anesthesia, and 2 other interventions for Diabetes Mellitus and Local Anesthesia. Completed, enrolled 256 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether 2% lidocaine (L) + clonidine (C) (15 mcg/ml) as a vasoconstrictor achieves efficient (equal or better parameters of intraoral local anesthesia in comparison to 2% lidocaine + epinephrine (E) (1:80 000)) and safe (stable cardiovascular parameters - systolic, diastolic, mean blood pressure and heart rate) intraoral local anesthesia in patients with Diabetes mellitus type 2.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDiabetes Mellitus, Local Anesthesia
CountriesSerbia
Collaborators--

Timeline

Phase 3CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedFeb 26, 2015
Enrollment StartJun 1, 2013
Primary CompletionJan 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 11.3 years ago

Interventions

L+C maxillary anesthesiadrug

Maxillary anesthesia obtained by 2% lidocaine + clonidine (15 mcg/ml)

L+C mandibular anesthesiadrug

Mandibular anesthesia obtained by 2% lidocaine + clonidine (15 mcg/ml)

L+E maxillary anesthesiadrug

Maxillary anesthesia obtained by 2% lidocaine + epinephrine (1:80 000)

L+E mandibular anesthesiadrug

Mandibular anesthesia obtained by 2% lidocaine + epinephrine (1:80 000)