At a glance
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The Effect of ERAS (Enhanced Recovery After Surgery) on Pancreaticoduodenectomy
In Brief
A clinical study evaluating ERAS perioperative management for Periampullary Tumor. Completed, enrolled 276 participants across 1 site.
Detailed Summary
Enhanced Recovery After Surgery (ERAS) is not the program that aim to reduce postoperative hospital stay, but the multimodal strategies that aim to attenuate the loss of, and improve the restoration of,functional capacity after surgery on evidence-based medicine. The benefits of ERAS is proved in many surgical procedures, such as upper gastrointestinal surgery and colorectal surgery. However, pancreaticoduodenectomy (PD, Whipple's operation) is still one of most complex abdominal surgery, and there is no evidence that ERAS is beneficial on PD. This study investigate the clinical effectiveness of ERAS on PD.
Study Details
Timeline
Interventions
* Preop Counseling * Preop biliary drainage (X) when Serum Total bilirubin \< 14.62mg/dl and cholangitis (-) * Preop enteral nutrition * Oral bowel preparation (mechanical bowel preparation ) (X) * Preop fasting \< 6 hours * Prevention of postoperative nausea and vomiting (PONV) (O) * Nasogastric intubation (X) * Near-zero fluid balance * Somatostatin analogues (X) * Postop routine artificial nutrition (X), soft diet at POD #2 * Audit * Other items are same as conventional