CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 24 enrolled
Drug / intervention
Levothyroxine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02374593
NCT02374593N/ACompleted
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Targeted Levothyroxine Dosing in Infants With Congenital Hypothyroidism

Erica Eugster·interventional·Posted Mar 2, 2015·Updated Oct 9, 2017

In Brief

A clinical study evaluating Levothyroxine and Ultrasound for Congenital Hypothyroidism. Completed, enrolled 24 participants across 1 site.

Detailed Summary

This is a clinical study comparing targeted levothyroxine dosing based on thyroid anatomy as visualized on ultrasound (normal vs. ectopic/sublingual vs. athyreosis) to empiric levothyroxine dosing in infants with congenital hypothyroidism. Patients enrolled in the study for targeted dosing will be compared to controls obtained by retrospective chart review. The main outcome is to determine if there is a difference in the frequency of over-treatment and under-treatment during the first 6 months of therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCongenital Hypothyroidism
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedMar 2, 2015
Enrollment StartMar 1, 2014
Primary CompletionMay 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 11.3 years ago

Interventions

Levothyroxinedrug

Levothyroxine dose will be adjusted at the first clinic visit based on thyroid anatomy on ultrasound.

Ultrasounddevice