At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 18 enrolled
Drug / intervention
Cocaine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer
In Brief
A Early Phase 1 clinical trial evaluating Cocaine and Sustained Release d-Amphetamine for Active Cocaine Users. Completed, enrolled 18 participants across 1 site.
Detailed Summary
Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate choice self-administration procedures between drug and a non-drug alternative reinforcer presented during maintenance on d-amphetamine, which has been previously shown to reduce cocaine use.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsActive Cocaine Users
CountriesUnited States
Collaborators--
Timeline
Early Ph 1CompletedFinished
201520162017201820192020202120222023202420252026
Enrollment StartFeb 2015
First PostedMar 2015
Primary CompletionApr 2018
TodayJul 2026
First PostedMar 9, 2015
Enrollment StartFeb 1, 2015
Primary CompletionApr 5, 2018
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 11.3 years ago
Interventions
Cocainedrug
Sustained Release d-Amphetaminedrug