At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 48 enrolled
Drug / intervention
OZ439 + TPGS +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase I Bioavailability Study of Selected Oral Prototype Granule Formulations of OZ439 in Healthy Subjects, to Evaluate the Pharmacokinetics of OZ439 When Co-Administered With Piperaquine Phosphate Tablets in the Fasted State
In Brief
A Phase 1 clinical trial evaluating OZ439 + TPGS, OZ439 Prototype 1, and 2 other interventions for Malaria. Completed, enrolled 48 participants across 1 site.
Detailed Summary
This is a single-centre, 2-part, randomised, single-dose parallel group study in healthy male subjects and female subjects of non-childbearing potential.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMalaria
CountriesUnited Kingdom
CollaboratorsQuotient Clinical
Timeline
Phase 1CompletedFinished
201520162017201820192020202120222023202420252026
First PostedMar 2015
Enrollment StartApr 2015
Primary CompletionJun 2015
TodayJul 2026
First PostedMar 13, 2015
Enrollment StartApr 1, 2015
Primary CompletionJun 1, 2015
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 11.3 years ago
Interventions
OZ439 + TPGSdrug
OZ439 Prototype 1drug
OZ439 Prototype 3drug
PQPdrug