CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 87 enrolled
Drug / intervention
Chemotherapy +8 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02392429
NCT02392429Phase 2Active
CompareCT.gov

Early Assessment of Treatment Response in AML Using FLT PET/CT Imaging

National Cancer Institute (NCI)·interventional·Posted Mar 19, 2015·Updated May 28, 2026

In Brief

A Phase 2 clinical trial evaluating Biospecimen Collection, Bone Marrow Aspiration, and 7 other interventions for Acute Myeloid Leukemia. Active but no longer recruiting, targeting 87 participants across 11 sites.

Detailed Summary

This phase II trial studies fluorothymidine F 18 (FLT) positron emission tomography (PET)/computed tomography (CT) in measuring response in patients with previously untreated acute myeloid leukemia. FLT is a radioactive substance that may "light up" where cancer is in the body. FLT is injected into the blood and builds up in cells that are dividing, including cancer cells. Diagnostic procedures, such as PET/CT, may help measure a patient's response to earlier treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Myeloid Leukemia
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
2015201620172018201920202021202220232024202520262027
First PostedMar 19, 2015
Enrollment StartApr 20, 2016
Primary CompletionDec 31, 2023
Study CompletionFeb 13, 2027
TodayJul 2, 2026
Enrollment to primary: 7.7 yearsPosted 11.3 years ago

Interventions

Biospecimen Collectionprocedure

Undergo blood sample collection

Bone Marrow Aspirationprocedure

Undergo bone marrow biopsy and aspiration

Bone Marrow Biopsyprocedure

Undergo bone marrow biopsy and aspiration

Chemotherapydrug

Given anthracycline IV

Computed Tomographyprocedure

Undergo FLT PET/CT

Cytarabinedrug

Given IV

Fluorothymidine F-18other

Undergo FLT PET/CT

Laboratory Biomarker Analysisother

Correlative studies

Positron Emission Tomographyprocedure

Undergo FLT PET/CT