At a glance
ClinicalIndex Comparison Record- ✓Age ≥18 years
- ✓Undergoing pancreaticoduodenectomy, partial or complete pancreatectomy, or duodenal ampullectomy
- ✓For ductal adenocarcinoma, IPMN, pancreatic neuroendocrine tumors without invasive component, or other benign pancreatic disease
- ✕Metastatic disease or disease precluding resection
- ✕Neoadjuvant chemotherapy or radiation within 6 months (first and second part of study)
- ✕Neoadjuvant radiation within 6 months (third part of study)
- ✕INR >2
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Interrogation of Exosome-mediated Intercellular Signaling in Patients With Pancreatic Cancer
In Brief
An observational study for Pancreatic Cancer and Benign Pancreatic Disease. Currently recruiting, targeting 181 participants across 1 site.
Detailed Summary
The purpose of this study is to isolate and analyze exosomes, which are tiny carriers of important proteins and nucleic acids that serve as messenger systems in the blood and tissue. Blood and tissue from patients with pancreatic cancer will be compared with blood and tissue from patients with noncancerous pancreatic disease. Including patients without cancer will allow the investigators to establish "normal" values, which currently do not exist. The investigators will then look to see whether exosome activity has a connection to disease recurrence and outcomes in patients. The results of this study will be the basis for future studies exploring this area.