CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
platelet-rich fibrin +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02397122
NCT02397122N/ACompleted
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The Adjunctive Effect of Platelet Rich Fibrin to Connective Tissue Graft in the Treatment of Buccal Recession Defects. Results of a Randomized Parallel Group Controlled Trial

Kırıkkale University·interventional·Posted Mar 24, 2015·Updated Oct 26, 2018

In Brief

A clinical study evaluating platelet-rich fibrin, connective tissue graft, and 1 other intervention for Gingival Recession. Completed, enrolled 40 participants.

Detailed Summary

The aim of the trial is to evaluate the effectiveness of coronally advanced flap (CAF)+connective tissue graft(CTG)+platelet-rich fibrin(PRF) combination in Miller I and II recession treatment by comparing with CAF+CTG. 40 patients were surgically treated either with CAF+CTG+PRF (test group) or CAF+CTG (control group). Clinical parameters of plaque index (PI), gingival index (GI), vertical recession (VR), probing depth (PD), attachment level (AL), keratinized tissue width (KTW), horizontal recession (HR), MGJ localization (L-MGJ), tissue thickness (TT) were recorded at baseline, 3 months (PS1) and 6 months (PS2) post-surgery. Root coverage (RC), complete RC (CRC), attachment gain (AG), and keratinized tissue change (KTC) were also calculated.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGingival Recession
Countries--
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 24, 2015
Enrollment StartFeb 1, 2013
Primary CompletionDec 1, 2013
Study CompletionMay 1, 2014
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 11.3 years ago

Interventions

platelet-rich fibrinbiological

autologous platelet-rich fibrin was isolated from venous blood of each patient by defined centrifugation methods

connective tissue graftprocedure

connective tissue graft was harvested from the palatal region of each patient by single incision method

coronally advanced flapprocedure

buccal gingival flap was raised by sharp-blunt-sharp dissection and positioned coronally to cover connective tissue graft (and platelet-rich fibrin gel)