CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 100 enrolled
Drug / intervention
IV dexamethasone +3 moredrug
Likely dose
IV dexamethasone 0.15 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02401529
NCT02401529Phase 2Completed
CompareCT.gov

Effect of Steroids on Post-tonsillectomy Morbidities

King Fahd General Hospital·interventional·Posted Mar 30, 2015·Updated Jul 15, 2015

In Brief

A Phase 2 clinical trial evaluating IV dexamethasone, Oral prednisolone, and 2 other interventions for Postoperative Pain and Postoperative Nausea and Vomiting. Completed, enrolled 100 participants.

Detailed Summary

This study aims to evaluate the effect of postoperative systemic rapid onset and short acting dexamethasone followed by a tapering dose of oral prednisolone on post-tonsillectomy morbidities. Half of the patients who comply with the inclusion criteria were selected to receive a single postoperative dose of intravenous dexamethasone followed by oral steroids; the second group received placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostoperative Pain, Postoperative Nausea and Vomiting
Countries--
Collaborators--

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 30, 2015
Enrollment StartJan 1, 2013
Primary CompletionMar 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 11.3 years ago

Interventions

IV dexamethasonedrug

0.15 mg/kg

Oral prednisolonedrug

0.25mg/kg/day for 7 days then tapering for next 7 days

Paracetamoldrug

acetaminophen 15 mg/kg/dose every 6 hours

IV salinedrug

IV saline