CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 27 enrolled
Drug / intervention
rAAV2tYF-CB-hRS1biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02416622
NCT02416622Phase 2Completed

A Multiple-Site, Phase 1/2, Safety and Efficacy Trial of a Recombinant Adeno-associated Virus Vector Expressing Retinoschisin (rAAV2tYF-CB-hRS1) in Patients With X-linked Retinoschisis

Beacon Therapeutics·interventional·Posted Apr 15, 2015·Updated Jun 12, 2023

In Brief

A Phase 2 clinical trial evaluating rAAV2tYF-CB-hRS1 for X-linked Retinoschisis. Completed, enrolled 27 participants across 9 sites.

Detailed Summary

This study will evaluate the safety and efficacy of a recombinant adeno-associated virus vector expressing retinoschisin (rAAV2tYF-CB-hRS1) in patients with X-linked retinoschisis. Up to 27 participants will be enrolled and 3 dose levels will be evaluated in a dose escalation format.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedApr 15, 2015
Enrollment StartMay 1, 2015
Primary CompletionApr 1, 2019
Study CompletionMay 9, 2023
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 11.2 years ago

Interventions

rAAV2tYF-CB-hRS1biological

adeno-associated virus vector expressing retinoschisin