At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Local Heat Stress in Autonomic Failure Patients With Supine Hypertension
In Brief
A clinical study evaluating Passive heat stress and Control (non-heating) for Hypertension and 3 related conditions. Completed, enrolled 22 participants across 1 site.
Detailed Summary
Patients with autonomic failure are characterized by disabling orthostatic hypotension (low blood pressure on standing), and at least half of them also have high blood pressure while lying down (supine hypertension). Exposure to heat, such as in hot environments, often worsens their orthostatic hypotension. The causes of this are not fully understood. The purpose of this study is to evaluate whether applying local heat over the abdomen of patients with autonomic failure and supine hypertension would decrease their high blood pressure while lying down. This will help us better understand the mechanisms underlying this phenomenon, and may be of use in the treatment of supine hypertension.
Study Details
Timeline
Interventions
Passive heat stress will be applied with a commercial heating pad that covers all the abdomen and part of the torso to provide local heating at \~44ºC continuously for 2 hr.
Heating pad will be applied over the abdomen and part of the torso but it will be turned off.