CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50 enrolled
Drug / intervention
Bupivacaine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02420951
NCT02420951N/ACompleted

Local Injection of Local Anesthetic 24 Hours After Knee Replacement Surgery

Brigham and Women's Hospital·interventional·Posted Apr 20, 2015·Updated Jan 12, 2018

In Brief

A clinical study evaluating Bupivacaine and No Intervention for Arthroplasty, Knee and Pain. Completed, enrolled 50 participants.

Detailed Summary

The purpose of this study is to determine if an additional injection of local anesthetic immediately prior to removal of the local anesthetic infiltration catheter on postoperative day one is effective in increasing pain reduction, patient satisfaction or outcome measures following total knee replacement (TKR). It is hypothesized that an additional injection of 30ml of .5% bupivacaine solution immediately before infiltration catheter removal will provide pain reduction, patient satisfaction and outcome measures equal or superior to catheter removal with no additional injection. Patients who are undergoing unilateral total knee replacement (TKR) and choose to participate will be randomly assigned to a treatment group.Patients in group one (treatment group) will receive a 30ml dose of .5% bupivacaine solution injected into the local anesthetic infiltration catheter immediately prior to its removal on postoperative day one. Patients in group two (control group) will receive no additional medication during local anesthetic infiltration catheter removal.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedApr 20, 2015
Enrollment StartOct 5, 2015
Primary CompletionMar 22, 2016
Study CompletionDec 9, 2016
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 11.2 years ago

Interventions

Bupivacainedrug

Injection of local anesthetic immediately prior to catheter removal, 24 hours postop.

No Interventionother

No injection of local anesthetic immediately prior to catheter removal, 24 hours postop.