At a glance
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COcoa Supplement and Multivitamin Outcomes Study
In Brief
A Phase 4 clinical trial evaluating Cocoa extract, Multivitamin, and 2 other interventions for Cardiovascular Disease and Cancer. Completed, enrolled 21,442 participants across 2 sites.
Detailed Summary
The purpose of this study is to determine whether taking daily, dietary supplements of cocoa extract (containing cocoa flavanols and theobromine from the cocoa bean) and/or a standard multivitamin reduces the risk of developing cardiovascular disease (including heart attack, stroke, coronary revascularization, unstable angina or acute coronary syndrome (ACS) requiring hospitalization, carotid artery surgery, and peripheral artery surgery or angioplasty, and cardiovascular mortality) and cancer.
Study Details
Timeline
Interventions
2 capsules each day containing a total of 500 mg cocoa flavanols, including 80 mg (-)-epicatechin, and 50 mg theobromine
Multivitamin
Cocoa extract placebo
Multivitamin placebo