CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 267 enrolled
Drug / intervention
Aclidinium/Formoterol +1 moredrug
Likely dose
Aclidinium/Formoterol 12μgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02424344
NCT02424344Phase 4Completed

A Multiple Dose, Randomized, Double-blind, Placebo Controlled, Parallel Clinical Trial to Assess the Effect of Aclidinium Bromide/Formoterol Fumarate Fixed-dose Combination on Lung Hyperinflation, Exercise Capacity and Physical Activity in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

AstraZeneca·interventional·Posted Apr 23, 2015·Updated Oct 9, 2018

In Brief

A Phase 4 clinical trial evaluating Aclidinium/Formoterol and Placebo for Pulmonary Disease, Chronic Obstructive. Completed, enrolled 267 participants across 26 sites in 4 countries.

Detailed Summary

The present study is planned to evaluate the effect of the aclidinium bromide/formoterol fumarate 400/12 μg FDC BID on the hyperinflation, exercise endurance and physical activity in patients with moderate to severe COPD. Additionally, the effect of the behavioural intervention on top of aclidinium bromide/formoterol fumarate 400/12 μg will be assessed both on the exercise endurance and the physical activity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, Germany, Hungary, Spain
CollaboratorsMenarini Group

Timeline

Phase 4CompletedFinished
201520162017201820192020202120222023202420252026
First PostedApr 23, 2015
Enrollment StartApr 27, 2015
Primary CompletionJul 25, 2016
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 11.2 years ago

Interventions

Aclidinium/Formoteroldrug

Aclidinium bromide/Formoterol fumarate FDC 400/12μg dry powder for oral inhalation twice daily via Genuair inhaler

Placebodrug

Dose-matched placebo dry powder for oral inhalation twice daily via Genuair inhaler