CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 enrolled
Drug / intervention
Corneal reshaping/crosslinking (CRXL) +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02425150
NCT02425150N/ACompleted
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Treatment of Keratoconus With Advanced Corneal Crosslinking

Umeå University·interventional·Posted Apr 23, 2015·Updated Dec 11, 2020

In Brief

A clinical study evaluating Corneal reshaping/crosslinking (CRXL) and Corneal Crosslinking (CXL) for Keratoconus. Completed, enrolled 120 participants.

Detailed Summary

The purpose of this study was to determine whether mechanical compression of the cornea during corneal crosslinking for keratoconus using a sutured rigid contact lens can improve the optical outcomes of the treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKeratoconus
Countries--
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedApr 23, 2015
Enrollment StartOct 1, 2009
Primary CompletionOct 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5 yearsPosted 11.2 years ago

Interventions

Corneal reshaping/crosslinking (CRXL)procedure

The keratoconus cornea is treated with epithelial debridement in local anesthesia, is soaked in Riboflavin by repeated topical application during 30 minutes. A flat, rigid contact lens is sutured to the cornea and the cornea and is then irradiated with ultraviolet light 5.4 J/cm2 during 30 minutes.

Corneal Crosslinking (CXL)procedure

The keratoconus cornea is treated with epithelial debridement in local anesthesia, is soaked in Riboflavin by repeated topical application during 30 minutes. The cornea and is then irradiated with ultraviolet light 5.4 J/cm2 during 30 minutes.