CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 16 enrolled
Drug / intervention
Pemetrexed Disodium +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02426658
NCT02426658Phase 2Completed

A Pilot Study Evaluating Pemetrexed in ECOG Performance Status 3 Patients With Stage IV Non-squamous Non-small Cell Lung Cancer

Wake Forest University Health Sciences·interventional·Posted Apr 27, 2015·Updated Oct 12, 2023

In Brief

A Phase 2 clinical trial evaluating Laboratory Biomarker Analysis, Pemetrexed Disodium, and 1 other intervention for Stage IV Non-Small Cell Lung Cancer. Completed, enrolled 16 participants across 1 site.

Detailed Summary

This pilot phase II trial studies how well pemetrexed disodium works in treating patients with stage IV non-small cell lung cancer and an Eastern Cooperative Oncology Group (ECOG) performance status of 3. Performance status means how well patients are able to perform daily activities and care for themselves. Patients with a performance status of 3 have a limited ability to move around. Currently, only patients who are able to perform most of their daily activities may receive chemotherapy, due to the side effects it may cause. Pemetrexed disodium causes fewer side effects than many chemotherapy drugs and may help treat patients with stage IV non-small cell lung cancer and a lower performance status.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedApr 27, 2015
Enrollment StartMay 1, 2015
Primary CompletionApr 19, 2018
Study CompletionOct 7, 2022
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 11.2 years ago

Interventions

Laboratory Biomarker Analysisother

Correlative studies

Pemetrexed Disodiumdrug

Given IV

Quality-of-Life Assessmentother

QOL studies