CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 280 enrolled
Drug / intervention
Dexamethasone +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02426736
NCT02426736Phase 4Completed

Effect of Dexamethasone Dose and Route on Duration of Interscalene Brachial Plexus Block for Outpatient Arthroscopic Shoulder Surgery - A Randomized Controlled Trial

University of Manitoba·interventional·Posted Apr 27, 2015·Updated Oct 26, 2017

In Brief

A Phase 4 clinical trial evaluating Dexamethasone, Bupivacaine, and 1 other intervention for Pain, Postoperative and Disorder of Shoulder. Completed, enrolled 280 participants across 1 site.

Detailed Summary

In this factorial design study, 280 participants having outpatient, arthroscopic shoulder surgery will be randomized into 4 equal sized groups. All participants will receive a standardized interscalene brachial plexus block and 4mg or 8mg of dexamethasone given by the intravenous or perineural (by the nerve with the nerve block) route just prior to their surgery. The purpose of this study is to determine which dose and route of dexamethasone provides the longest duration of pain control and the fewest side effects after surgery. The investigators hypothesize that giving dexamethasone by the perineural route, and by higher doses, will result in the longer durations of pain control, without increased side effects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada
Collaborators--

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedApr 27, 2015
Enrollment StartJun 25, 2015
Primary CompletionJul 12, 2016
Study CompletionJan 12, 2017
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 11.2 years ago

Interventions

Dexamethasonedrug

Bupivacainedrug

Interscalene brachial plexus blockprocedure

Performed with real time ultrasound guidance.