CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 88 enrolled
Drug / intervention
Intuvax (INN: ilixadencel) +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02432846
NCT02432846Phase 2Completed

An Open-label, Randomized, Controlled, Multicenter, Phase II Study Evaluating Safety and Efficacy of Intratumorally Administered Intuvax Pre-nephrectomy Followed by Sunitinib Post-nephrectomy, Compared to Sunitinib Post-nephrectomy in Metastatic Renal Cell Carcinoma Patients

Mendus·interventional·Posted May 4, 2015·Updated Aug 22, 2022

In Brief

A Phase 2 clinical trial evaluating Intuvax (INN: ilixadencel) and Sunitinib for Renal Cell Carcinoma, Metastatic. Completed, enrolled 88 participants across 28 sites in 9 countries.

Detailed Summary

The purpose of this study is to compare tumor response, progression free survival (PFS) and overall survival (OS) in newly diagnosed mRCC patients treated with Intuvax (INN: ilixadencel) pre-nephrectomy followed by Sunitinib post-nephrectomy vs Sunitinib post-nephrectomy patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCzechia, France, Hungary, Latvia, Poland, Spain, Sweden, United Kingdom, United States

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedMay 4, 2015
Enrollment StartApr 1, 2015
Primary CompletionJan 31, 2021
TodayJul 2, 2026
Enrollment to primary: 5.8 yearsPosted 11.2 years ago

Interventions

Intuvax (INN: ilixadencel)biological

Therapeutic dose (10 million cells/dose): allogeneic, pro-inflammatory dendritic cells.

Sunitinibdrug

Cytostatic/cytotoxic drug: protein kinase inhibitor .