At a glance
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Simultaneous Aerobic Exercise and Memory Training in Older Adults With Subjective Memory Complaints
In Brief
A clinical study evaluating simultaneous aerobic exercise, sequential aerobic exercise, and 1 other intervention for Memory Impairment. Completed, enrolled 60 participants across 1 site.
Detailed Summary
This pilot study is a first step in a rapidly growing area of clinical research to create the most effective means to combat age-related losses in cognitive function through preventive lifestyle strategies such as physical exercise and memory training. This study will develop innovative simultaneous exercise and memory training programs in non-demented volunteers with subjective memory complaints (controls or MCI). Our primary goal is to assess the cognitive impact of 4-week memory training programs done twice weekly: 1. during simultaneous aerobic exercise (SIM-AR-MET), 2. sequentially after aerobic exercise (SEQ-AR-MET), or 3. without aerobic exercise (replaced with sequential stretching and toning) (SEQ-ST-MET). The investigators will also measure potential metabolic (e.g., glucose, lipid panel) and molecular (serum BDNF) mediators of observed cognitive changes in a subset of participants (those at the UCLA CTRC/IPCN site).
Study Details
Timeline
Interventions
stationary bicycling at 65% of heart rate reserve for 30 minutes while receiving memory training.
stationary bicycling at 65% of heart rate reserve for 30 minutes followed by memory training.
anaerobic stretching and toning followed by memory training.