At a glance

ClinicalIndex Comparison Record

N/ACompleted· 19 enrolled

Drug / intervention

Real tDCS +1 moreother

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02436915

NCT02436915N/ACompleted

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The Effects of Noninvasive Brain Stimulation on Physical and Mental Functioning in Older Adults

Hebrew SeniorLife·interventional·Posted May 7, 2015·Updated Jun 5, 2019

In Brief

A clinical study evaluating Real tDCS and Sham tDCS for Aging. Completed, enrolled 19 participants across 1 site.

Detailed Summary

The objective of this study is to determine whether augmentation of prefrontal brain excitability using noninvasive transcranial direct current stimulation (tDCS) lessens the severity of the symptom triad associated with cerebral microvascular disease (CMD); that is, slow gait, cognitive dysfunction and depressive symptoms. Investigators will complete this objective by conducting a pilot, double-blinded randomized controlled trial of a 10-day intervention of real versus sham tDCS in 40 subjects.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsAging

CountriesUnited States

CollaboratorsBeth Israel Deaconess Medical Center, The Falk Medical Research Trust, Bank of America, N.A. Trustee

Timeline

N/ACompletedFinished

20162017201820192020202120222023202420252026

First PostedMay 2015

Enrollment StartJun 2015

Primary CompletionOct 2016

Study CompletionDec 2016

TodayJul 2026

First PostedMay 7, 2015

Enrollment StartJun 1, 2015

Primary CompletionOct 1, 2016

Study CompletionDec 1, 2016

TodayJul 2, 2026

Enrollment to primary: 1.3 yearsPosted 11.2 years ago

Interventions

Real tDCSother

Transcranial direct current stimulation (tDCS) enables noninvasive, selective and sustained modulation of cortical activation. tDCS works by sending low-level currents between two or more scalp electrodes, which alters brain polarity and thus, perfusion and cortical excitability.

Sham tDCSother

For sham tDCS, current will only be applied for the first 60 seconds of each 20 minute session. This is a reliable sham control as sensations arising from tDCS diminish considerably after the first minute of stimulation.