At a glance
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Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.
In Brief
A Phase 2 clinical trial evaluating Hydromorphone for Pain. Completed, enrolled 35 participants across 1 site.
Detailed Summary
Intranasal hydromorphone has been shown to be effective in reducing acute pain in adults. It has not been previously studied in children, but may be a viable option for effectively and safely reducing pain in children by administering an analgesic by the intranasal route. This study will be a prospective, open-label pilot study of intranasal hydromorphone in children with moderate to severe acute pain presenting to the pediatric emergency department. The investigators aim to describe the amount of pain reduction associated with intranasal hydromorphone, and to determine the optimal dose of intranasal hydromorphone associated with a clinically meaningful improvement in acute pain.
Study Details
Timeline
Interventions
To be administered by intranasal route using mucosal atomization device.