CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 102 enrolled
Drug / intervention
Exerciseother
Likely dose
Not stated in record
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Search/NCT02439112
NCT02439112N/ACompleted

Early Initiated Individualized Physical Training in Newly Diagnosed Multiple Myeloma Patients; Effects on Physical Function, Physical Activity, Quality of Life, Pain, and Bone Disease.

Zealand University Hospital·interventional·Posted May 8, 2015·Updated Dec 17, 2020

In Brief

A clinical study evaluating Exercise for Multiple Myeloma. Completed, enrolled 102 participants across 1 site.

Detailed Summary

The overall aim is to examine whether early initiated, individualized exercise training in patients newly diagnosed with multiple myeloma, irrespective of age and current performance status, will be beneficial for the patients´physical function, level of physical activity and quality of life, pain and bone disease. The investigators will examine the effect of supervised in-hospital exercise training sessions combined with home-based exercise training, initiated at time of diagnosis. The outcomes of interest are physical function, level of physical activity, QOL, pain and bone disease. Furthermore, to describe the disease in patients with newly diagnosed MM in relation to physical function, level of physical activity, QOL, pain and bone condition at time of diagnosis. The investigators hypotheses are: * Individualized exercise starting at time of diagnosis will have positive effects on physical function, physical activity, QOL and pain. * Individualized exercise starting at time of diagnosis will have positive effects on bone disease (bone markers), bone mineral density (BMD) and lean body mass. * A higher level of physical function is associated with a higher level of physical activity, less pain, better QOL, and higher BMD and lean body mass.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesDenmark

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 8, 2015
Enrollment StartMay 1, 2015
Primary CompletionFeb 5, 2020
Study CompletionDec 1, 2020
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 11.2 years ago

Interventions

Exerciseother

8 supervised in-hospital training sessions in a period of 10 weeks. On a general level, the intervention will follow the Danish physical activity guidelines for elderly \>65 years (Sundhedsstyrelsen 2011, see link) and consist of strength exercise, aerobic exercise and physical activity. Bone involvement will taken into consideration in all parts of the exercise program by excluding and including specific exercises and mode of exercise according to location and extent of bone involvement (Galvão 2011; Cormie 2013)